LPG has been well known as a clean alternative fuel for vehicles. As a fundamental study on liquid phase LPG injection (hereafter LPLI) system application to heavy-duty engine, engine output and combustion performance were investigated with various operating conditions using a single cylinder engine equipped with the LPLI system. Experimental results revealed that no problems were occurred in application of the LPG fuel to heavy-duty engine, and that volumetric efficiency and engine output, by 10% approximately, were increased with the LPLI system. It was resulted from the decrease of the intake manifold temperature through liquid phase LPG fuel injection. These results provided an advantage in the decrease of the exhaust gas temperature, in the control of knocking phenomena, spark timing and compression ratio. The LPLI engine could normally operated under $lambda$=1.5 or EGR 30% condition. The optimized swirl ratio for the heavy duty LPG engine was found around R_s$ = 2.0.