누에 체성분이 생쥐의 혈액성분에 미치는 영향을 조사하고자 5령 3일된 누에를 70% 알콜로 추출한 활성물질을 생쥐(C57BL/6)의 복강에 20mg/kg/day의 농도로 15일 동안 투여한 다음, 24시간 후에 실험동물을 $CO_2$로 회생시켜 체중변화와 혈액성분의 생화학적인 지표를 조사하였다. 그 결과, 체중과 혈중의 albumin, GOT, GPT 및 LDH의 함량은 누에추출물을 투여함에 따라 차이가 없었으나 creatinine, cholesterol, triglyceride, glucose, BUN 및 ALP의 함량은 감소하였다.
To investigate the effects of silkworm-extract (SE) on the blood components levels in mice, we extracted the physiologically active substance by 70% ethanol from 5th instar 3rd day silkworm. Mice were administered intraperitoneally with the SE (20mg/kg/day) for 15 days. Animals were sacrificed with $CO_2$ gas 24 hr after the last SE treatment. Then, we investigated the body weight and biochemical markers on blood components levels in mice. The results, body weight and albumin, GOT, GPT, LDH of blood were not changed by the SE treatment to mice. But creatinine, cholesterol, triglyceride, glucose, BUN, ALP of blood were significantly decreased by the SE treatment to mice.
