The purpose of this study was to test the effect of the health education on college students. The content of the health education was consisted of significance of health, smoking, alcohol use and sexuality, birth control, exercise and nutrition, chronic illness, contagious disease, stress management. Two groups non-equivalent to pre and post test quasi-experimental research design were used in this study. The total number of subjects were 174 college students who did not have a health related major. The experimental group attended this health education program for 16 weeks and the control group attended other liberal arts and science classes for 16 weeks. Data were analysed with the SPSS window program. The homogeneity between the experimental and the control group pretest data was tested by $X^2$ test and t-test. The differences in stress, self-esteem, general self-efficacy, locus of control and health promoting behaviors after the health education were tested with the repeated measure ANOVA. The results were as follows: 1. There was no significant difference in general characteristics, stress, self- esteem, general self-efficacy, locus of control and health promoting behaviors between the two groups before the health education. 2. There was a significant difference in stress(p= .000) and health promoting behavior (p= .000) between the two groups after the health education. 3. There was no significant difference in self-esteem(p= .531), self-efficacy(p= .110) and locus of control between the two groups after the health education. From the results above, it can be concluded that this health education for the college students was effective to relieve stress and improve health promoting behaviors. The above results suggest that repeated studies are needed for another college students and various health education programs should be developed to promote the health of the populace considering many health related concepts.