The CFD analysis of the three-dimensional turbulent flow in the impeller and diffuser of an axial flow pump was performed. Not only the design point but also the off-design points were computed. The results were compared with available experimental data in terms of head generated. At the design point, the analysis accurately predicted the experimental head value. In the range of the higher flow rates, the results were also in very good agreement with the experimental data, not only in absolute value but also in term of slope. Although experimental data to be compared were not available in the range of the lower flow rates, the results well described the S-shape performance curve of the axial pump characteristic.