In order to study the effect of the isometric exercises on the flexibility. the strength and the waist and hip circumferences, 10 female university students who aged 22.10 ${pm}$ 1.10 years were measured by sit-up for strength, and trunk flexion test and trunk lifting for flexibility, and also measured by waist and hip circumferences before and during, and after the Swiss ball exercise program. Statistical analysis was performed using SPSS/PC WIN 7.0 version. and one-way repeated ANOVA Test, The results of the test were as shown; We found that the number of performing sit-up was increased. and the trunk flexion test and trunk lifting was increased, and the waist and hip circumferences were increased after the 6 weeks Swiss ball exercise program. These findings indicate that Isometric exercise using Swiss ball could be beneficial to the low back pain patients due to the effect of increasing strength and flexibility of the patients.