There are many studies which reveal most of the accidents are related to pilot errors. Looking at each phase of flight, the accidents which occurred at the segments of take-off and landing consist of 70%, cause these phases need precise cooperations between pilots and ATC specialists to make sure every instructions understood and instruments to be normal. Therefore, the accidents of these phases leave great regrets and the price was enormous to people and equipments. Until now, most of the studies investigate the accident itself and very few show the relationships between pilots and air traffic controllers. This study analyzes the impacts of inter-dependence to mutual trust, cooperations and relationship efficiency between them who play important parts in flight. Based upon the findings, the inter-dependence has an effect on mutual trust and the latter influences to cooperations. Also, mutual trust and cooperations have a leading role in the relationship efficiency. It implies that mutual trust, cooperations, and the degree of inter-dependence are important factors to improve the relationships between them.