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Anti-platelet Effect of the Phenolic Constituents Isolated from the Leaves of Magnolia obovata
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  • Anti-platelet Effect of the Phenolic Constituents Isolated from the Leaves of Magnolia obovata
  • Anti-platelet Effect of the Phenolic Constituents Isolated from the Leaves of Magnolia obovata
저자명
Pyo. Mi-Kyung,Koo. Yean-Kyoung,YunChoi. Hye-Sook
간행물명
Natural product sciences
권/호정보
2002년|8권 4호|pp.147-151 (5 pages)
발행정보
한국생약학회
파일정보
정기간행물|ENG|
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이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
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기타언어초록

In the course of our work on anti-platelet constituents from plants, eight phenolic compounds, $({pm})-syringaresinol$ (1), 4-hydroxybenzaldehyde (2), 4-hydroxybenzoic acid (3), vanillic acid (4), 4-hydroxy cinnamic acid (5), quercetin 3-O-rhamnoside (6), rutin (7), and quercetin $3-(2^G-rhamnosylrutinoside)$ (8) were isolated from the methanol extract of the leaves of Magnolia obovata. The compounds were identified based on the spectroscopic data. Compound 2, 3, 5, 6, 7 and 8 were isolated for the first time from genus Magnolia. 1 and 6 showed same order of inhibitory potencies as acetylsalicylic acid (ASA) to rat platelet aggregation induced by all the stimulators tested. The remaining six compounds showed only mild effects.