Abnormal weather in four season(歲時不正之氣) is pathogen factor of deficiency type(虛邪). It is the main contents of this chapter that, at the state of the abnormal wind in four season, it is easy to fall ill the human body. In the head, it describes Malara and Qi in the human hody(人氣). In the middle, it describes Qi in the human body and Qi in universe(天氣). In the end it deals with Qi in universe. The main contents are as follow. In the first chapter, it describes contents that the cause which the time of Malaria attack is different, are closely connected with winning and waxing between pathogenic factor and vita Qi(邪正相搏). In the second chapter, it describes contents that whether four season and eight wind as pathogen(四時八風邪氣) fall ill the human body or not, a level of invade human, rapid or late of the outbreak of illness, depend upon strong or weak of constitution(人體 强弱) and opening and closing of striae of skin(주理 開闔). In the third chapter, it discussed contents that we can presume climatic change in four season and analyze epidemicity of disease through the theory of Googungpalpoong(九宮八風).