This study reports the analysis of the pressure drop characteristics for the air-particle flow in powder transport piping system. The pressure drop characteristics of air-particle flow in piping system is not well understood due to the complexity of particles motion mechanism. Particles or powders suspended in air flow cause the increase of the pressure drop and affect directly the transportation efficiency. In this study, the pressure drop in powder transport piping system with straight and curved pipes is analyzed for the interactions of air flow and particle motion. The total pressure drop increases with increasing of the pipe length, the mixture ratio, and the friction factor of particles due to the increasing friction loss by air and particles in a coal piping system. For the coal powders of $74{mu}m$ size and powder-to-air mass mixture ratio of 0.667, the total pressure drop by the consideration of powders and air flow is $30\%$ higher than that of air flow only.