This paper describes an integrated approach process to carry out pre-test, model correlation and updating analysis on the sub-frame of a vehicle. In this study, it was found that the modal test could be more efficient when the exciting point was selected on the area with high driving point residue. Such area could be located with the aid of finite element modal analysis. The model correlation was appraised in conjunction with the modal parameters between modal test and finite elements analysis. Also, the finite element model updating was obtained the good resultant using the iteration method based on sensitivity analysis results that carried out the variation of natural frequencies and MAC for the material properties. Finally, optimization of vehicle subframe was carried out the analysis of core location and physical properties by tow steps.