This gaper discusses a multidisciplinary design optimization of the engine mounting system to improve the ride quality of a vehicle and to remove the possibility of the resonance between the powertrain system and vehicle systems. The driveline model attempts to support engine mount development by providing sufficient detail for design modification assessment in a modeling environment. Design variables used in this study are the locations, the angles and the stiffness of an engine mount system. The goal of the optimization is both decoupling the roll mode ova powertrain and minimizing the vibration transmitted to the vehicle including the powertrain, simultaneously. By applying forced vibration analysis for vehicle systems and mode decouple analysis for the engine mount system, it is shown that improved optimization result is obtained.