A study on architecture of new parallel interference canceller which can be applied for reverse link of next generation mobile communication system supporting multi-rate is performed on this paper. The proposed method adopts new algorithm which can be applied for multi-rate system to reduce multiple access interference (MAI) which cause performance degradation of CDMA system and limit of channel capacity. The proposed system is evaluated by simulation results under various conditions. As a result, performance enhancement is achieved compared to existing conventional interference cancellers. Although the amount of calculation is increased, we can find that the performance is improved generally.