Cotton fabric was treated with TiO$_2$-PEG600 mixed solution by pad-dry-cure and wet-fixation process to improve the performance properties as well as antibiosis effect and its laundering durability. In this paper, the effects of concentration of $TiO_2/PEG$ and fixation process were investigated on laundering durability and properties of cotton fabric treated with glyoxal. As the concentration of $TiO_2/PEG$ increased fixation, W.I., K/S of treated cotton fabric increased. Application of wet-fixation method provided a further improvement in fixation, laundering durability of treated cotton fabric.