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광감제가 코팅된 자성유체의 제조와 광역학 치료용 장치의 구성
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  • 광감제가 코팅된 자성유체의 제조와 광역학 치료용 장치의 구성
저자명
권순광,김종오,김종희,Gwon. Sun-Gwang,Kim. Jong-O,Kim. Jong-Hui
간행물명
한국재료학회지
권/호정보
2002년|12권 3호|pp.215-219 (5 pages)
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한국재료학회
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이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
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For the purpose of annihilating tumor in body, hematoporphyrin as a photosensitizer was coated onto magnetic particles of $Fe_3O_4$ prepared by coprecipitation which could be concentrated around the tumor by magnetic field. The photosensitizer was applied differently before, during and after adsorbing the 1st surfactant on the particles. Its added amount was $5{ imes}10^{-4}/mol$, and the coating reaction proceeded at temperatures of 60, 70 and 8$0^{circ}C$. The amounts of photosensitizer coated on the magnetic particles were obtained by calculating an optical density with the maximum UV spectrum. As a result of the UV analysis, the coating amount of photosensitizer increased with higher reaction temperatures. When applied at 8$0^{circ}C$ after adsorbing the 1st surfactant, the photosensitizer was coated with a maximum value of $3.8{ imes}10^{-3}/mo1/$ell$$</TEX>. The TGA analysis revealed that the ferrofluids included the particles of 30.115 g/$ell$. It was suggested that the magnetite particles was coated with photosensitizer of $1.26{ imes}10^{-4}/mo1/g$. A small-sized device for magnetic field and light emission was designed, in which LED sheets coverts the permanent magnet of Nd-Fe-B. The LED sheet was connected in series circuit and also protected with a silicon tube. The power was supplied with rechargable battery of 9V and 100-120mA.