This study was to evaluate mechanical properties and toughness of the Al5083-O aluminum alloy welding zone according to the mixing shield gas ratio and heat input change. The GMA(Gas Metal Arc) welding of the base metal was carried out with four different mixing shield gas ratios(Ar100%+He0%, Ar67%+He33%, Ar50%+He50%, and Ar33%+He67%) and three different heat inputs(low, medium, and high). To investigate the Charpy absorbed energy of the weld zone, the specimens were divided base metal, weld metal, fusion line, and HAZ notched specimen according to the worked notch position. The different gas ratio and heat input had little effect upon the tensile strength. But Ar33%+He67% mixture had the greatest mechanical properties considering that the more He gas ratio concentrations, the higher yield strength and elongation. The maximum load and displacement of the weld metal notche specimen was so much low more than that of the base metal, but fusion line and HAZ notched specimens showed almost same regardless of the mixing shield gas ratio and heat input. The Charpy absorbed energy was lowest in weld metal notched specimen, and increased in the fusion line, and HAZ notche specimen in order. Ar33%+He67% mixture had the greatest toughness considering that the more He gas ratio, the higher absorption energy.