This study reviews and compares the selection procedures for science and technology topics to predict mid- and long-term trends in science and technology development in Korea, Japan, and the United Kingdom. It then identifies science and technology topics and future technologies for the third science and technology foresight of Korea. In Japan and the United Kingdom, non-technological topics that reflect socioeconomic needs are also select-ed along with technological ones. This study provides the following policy implications to enhance reliability and effectiveness of the third science and technology foresight of Korea. First, selection of science and technology topics should coincide with the national goal, taking into account development trends in science and technology and socioeconomic needs. Second, the current prediction methodologies such as "delphi" do not fully consider future uncertainties in science and technology development. A scenario method is, for example, needed to present coherent pictures of alternative futures. finally, the third technology foresight should select and include topics that reflect domestic conditions and global trend in technological progress. This study suggests 117 topics for the third science and technology foresight.foresight.