To minimize the size of transformer volume, the operating frequency of ferrites cores increasing. The power loss of Mn-Zn ferrites comprises hysteresis loss, eddy current loss and residual loss. In the range more then 500 KHz, the total power loss is mainly due to the residual loss. The power loss increase with the frequency 3rd power. To minimize residual loss as well as eddy current loss, the microstructure should have small grain and high density, It should be noted that as the product of resonance frequency and static permeability increase, the power loss decrease at high frequency region.