The vibrational system of this study is consisted of a cantilever pipe conveying fluid, the moving masses upon it and an attached tip mass. The equation of motion is derived by using Lagrange equation. The influences of the velocity and the number of moving masses and the velocities of fluid flow in the pipe have been studied on the natural frequency of a cantilever pipe by numerical method. As the size and number of a moving mass increases, the natural frequency of cantilever pipe conveying fluid is decreased. When the first a moving mass Is located at the end of cantilever pipe, the increasing of the distance of moving masses make the natural frequency increase at first and third mode, but the frequency of second mode is decreased. The variation of natural frequency of the system is decreased due to increase of the number of a moving mass. The number and distance of moving masses effect more on the frequency of higher mode of vibration