This paper describes the numerical determination of optimum blank diameter for sound material flow and high precise thread profile of a spindle screw through external thread rolling using two-three roll dies. Initial blank diameter affects the dimensional accuracy and surface finish qualities of a spindle screw in thread rolling process, therefore it is very important to determine the optimum blank diameter in thread rolling process. In order to determine the optimum blank diameter, this paper suggests the calculation method of initial bland diameter considering the real shape of tooth. The finite element code DEFORM is applied to analyze the metal flow of tooth, and these analytical results are verified by thread rolling experiment for spindle screw.