As automotive manufacturers have taken a growing more interest in tailored sheet metals for improving the rigidity, weight reduction, crash durability, and cost saving application of the tailored sheet metals to automotive bodies has been resently increased greatly. In this study, we investigated the characteristics of fatigue crack initiation behavior of laser welded sheet use for vehicle body panel. We experimented three types of specimens which were machined of the same base metal : one is 1.4㎜ thick, another is 1.6㎜ thick, the others is laser welded of the 1.4mm thick specimen and 1.6㎜ thick specimen. The results indicated that laser welded metal (1.4＋1.6㎜) is the best one for fatigue strength and fatigue life.