Case 1 was showed severe caughing and nasal discharge, who was one of 5-month-old 18 male sheep taking inspection for MCF experiment. Pathological examination of case 1 was conducted. Macroscopic observations were the foamy sticky fluids in nasal and tracheal cavity, the grey spots with 2-4 mm diameter on the surface of lung. Histopathological observations were severe eosinophil and other round cell infiltration in general organs including lung, trachea, small intestine, large intestine, liver. Also, in the lung, there were parasite-cutting lesions in some alveolar spaces and bronchioles. Following these observations, case 1 was diagnosed as ovine lungworm infection.