Artificial Neural Networks (ANN) have the capability to develop functional relationships between input-output patterns obtained from any source. Thus ANN can be conveniently used to develop a generalised relationship from limited and sometimes inconsistent data, and can therefore also be applied to tackle the data obtained from wind tunnel tests on building models with large number of variables. In this paper ANN model has been developed for predicting wind induced pressures in various zones of a Gable Building from limited test data. The procedure is also extended to a case wherein interference effects on a gable roof building by a similar building are studied. It is found that the Artificial Neural Network modelling is seen to predict successfully, the pressure coefficients for any roof slope that has not been covered by the experimental study. It is seen that ANN modelling can lead to a reduction of the wind tunnel testing effort for interference studies to almost half.