Mobile phone users have diversified human factors: their channel orientations are different, and the degrees of unwillingness to communicate vary. We examined the effect of human factors on the use of mobile phone, such as the diversity of mobile phone use, the appropriateness of mobile phone, and the aversion to mobile phone as well as the interpersonal communication network through mobile phone. For our sample we surveyed college students and their family members who are older than 400. We found that the more social presence a mobile phone user gets through the mobile phone, and the more familiar to the mobile phone he/she is, (1) the more diversified is the use of mobile phone service, (2) the higher is the level of acceptance of the mobile phone as an interpersonal communication media, and (3) the lower is the level of aversion to the mobile phone. In contrast, those who have some level of aversion to the face-to-face communication, seem to form very limited interpersonal communication network through mobile phone. Their use of mobile phone is also very limited.