Even in the world wide automobile companies where a few simple modules are put into practical use, the front subframe modules of which performances of durability, NVH and crash are significantly important are under planing. In this study, design technology for the automobile front subframe module, which consists of an engine, a transmission and steering parts, structural components (frame, upper arm, lower arm and brake etc.) and rubber components(engine mount, axle mount and rubber disc etc.), was developed. A FEM-based analytical approach was used to evaluate the multiaxial high cycle fatigue damage of the front subframe module. Strain-life fatigue database system and expert system for fatigue properties of welded materials were developed. Stiffness values of the various rubber bushes mounted on the front subframe were evaluated by experimental method and FEM. TWB(Tailor Welded Blank) technology was applied to forming the cross member of the front subframe. Performance evaluations in relation to NVH and crash were conducted by using CAE technologies.