Objectives: This study was designed to analyze the effectiveness of the diagnosis and treatments of Moya moya disease in oriental medicine. Results: This study showed that clinical symptoms of two Moya moya patients were improved by the diagnosis and treatments of oriental medicine. Conclusions: Diagnosis and treatment of two patients with Moya moya disease are accurate and effective. However, more cases are required to study in oriental medicine in order to prove the availability and to be applied universally.