This study tried to evaluate the difference of stress degree by Sasang constitution and lifestyle for workplace labors, and suggested the preventive oriental medicine approaches in occupational health area. 479 data for research were collected through the process of oriental health examination with questionnaire in workplace, and collected data were analyzed with frequency, crosstab, and Two-Way ANOVA. The results were as follows: 1) All subjects, total 479 were men, and constitutional distributions were 39.2% of Taeumin, 32.4% of Soumin, and 28.4% of Soyangin. The distributions of stress score were 13.2% of normal group, 13.4% of high risk group, and 73.5% of potential risk group. 2) There were no statistically significant differences for stress by constitution(p=0.085). By the results of optimal scaling and homogeneity analysis, Soyangin was close to potential risk group compared to other constitution, and Soumin and Taeumin were close to high risk and normal group, respectively. 3) For the difference of stress score by Sasang constitution and lifestyle, Soumin who exercised nearly everyday had the highest stress score with interaction in Factor 4 area(p<0.05), and there was no interaction in other area. 4) For the difference of PWI score by lifestyle, there were statistically significant differences for drinking(p<0.01), smoking(p<0.01), and obesity index(p<0.01)