The vibrational system of this study is consisted of a rotating cantilever pipe and the flow in the pipe. The equation of motion is derived by using Lagrange equation. The influences of the rotating angular velocity and the velocities of fluid flow in the pipe have been studied on the dynamic characteristics of a rotating cantilever pipe by numerical method. The tip-amplitude of axial vibration and maximum tip-deflection of axial direction of cantilever pipe are directly proportional to the velocity of fluid and rotating angular velocity of pipe In the steady state. respectively The bending tip-amplitude of cantilever pipe is inversely proportional to the velocity of fluid in the steady state. When the rotating angular velocity is 5 rad/s, the velocity of fluid increase with increasing the natural frequency of axial vibration at second mode and third mode, but the natural frequency axial direction of first mode is decreased. The natural frequency of lateral direction is decreased due to increase of the rotating angular velocity. It identifies that the Influence of velocity of fluid give much variation lower mode of vibration in lateral direction. And the Influence of velocity of fluid give much variation higher mode of vibration in axial direction.