The integrity of stiffened panels with stringers in airplane structure is generally enhanced by investigating the fatigue crack propagation behavior in detail and providing the technical methodology to deal with the propagating crack. This paper attempts to clarify the effect of load-ratio on the fatigue crack propagation rate and the fatigue life for the thin aluminum 2024-T3. Both the variable and the constant fatigue loading conditions are considered for the fatigue crack propagation behavior in stiffened panels with stringers.