The present study investigates the fire suppression characteristics using a water mist fire suppression system. Numerical simulations of fire suppression with water mist are performed with considering the interaction of fire plume and water droplet, droplet evaporation, and combustion of pool fire. The predicted temperature fields of smoke layer are compared with that of measured data. Numerical results agree with the experimental results within 5$^{circ}C$ in the case without water mist In the case of fire suppression with water mist, numerical results dose not predict well lot temperature field in the gradual cooling region after water mist injection. But the predicted results of initial fire suppression are in good agreement with that of measured data. The reason of the discrepancy between predicted and measured data is due to the variation of turning rate during the injection of water mist. The effect of burning rate on the fire suppression is left as future study.