In this paper, we propose an efficient mutual authentication and key distribution protocol for cdma2000 packet data service which uses Mobile U access method with DIAMETER AAA(Authentication, Authorization and Accounting) infrastructure. The proposed scheme provides an efficient mutual authentication between MN(Mobile Node) and AAAH(home AAA server), and a secure session-key distribution among Mobile If entities. The proposed protocol improves the efficiency of DIAMETER AAA and satisfies the security requirements for authentication and key distribution protocol. Also, the key distributed by the proposed scheme can be used to generate keys for packet data security over 1xEV-DO wireless interface, in order to avoid a session hijacking attack for 1xEV-DO packet data service.