Failure of a pipeline due to local wall thinning is getting more attention in the nuclear power plant industry. Although guidelines such as ANSI/ASME B31G and ASME Code Case N597 are still useful fer assessing the integrity of a wall thinned pipeline, there are some limitations in these guidelines. For instance, these guidelines consider only pressure loading and thus neglect bending loading. However, most Pipelines in nuclear power plants are subjected to internal pressure and bending moment due to dead-weight loads and seismic loads. Therefore, an assessment procedure for locally wall thinned pipeline subjected to combined loading is needed. In this paper, three-dimensional finite element(FE) analyses were performed to simulate full-scale pipe tests conducted for various shapes of wall thinned area under internal pressure and bending moment. Maximum moments based on true ultimate stress(${alpha}$$sub$u,t/) were obtained from FE results to predict the failure of the pipe. These results were compared with test results, which showed good agreement. Additional finite element analyses were performed to investigate the effect of key parameters, such as wall thinned depth, wall thinned angle and wall thinned length, on maximum moment. Also, the effect of internal pressure on maximum moment was investigated. Change of internal pressure did not show significant effect on the maximum moment.