A two-photon interference experiment is presented in which an entangled pair of photons generated from a parametric down-conversion was incident on two input ports of a Mach-Zehnder interferometer. The experiment was carried out using two photon coincidence detection with two detectors at the two output ports of the interferometer. The measured coincidence counts exhibit an interference effect with visibility of 0.75 at simultaneous inputs and 0.38 at inputs with different arrival times according to the degree of photon number entanglement.