Dimethyl Ether (DME) is an excellent alternative fuel that provides lower particulate matter (PM) than diesel fuel under the same engine operating conditions. Spray characteristical of DME in common rail injection system were investigated within a constant volume chamber by using the particle motion analysis system. The injector used in this study has a single hole with the different orifice diameter of 0.2, 0.3 and 0.4 mm. The injection pressure was fixed at 35MPa and the ambient pressure was varied from 0.6 to 1.5 MPa. Spray characteristics such as spray angle, spray tip penetration and SMD (Sauter mean diameter) were measured. Spray angle was measured at 30d$_{0}$, downstream of the nozzle tip. The measured spray angie increased with increase in the ambient pressure. Increase of the ambient pressure results in a decrease of spray penetration. The experimental result, of spray penetration were compared with the predicted one by theoretical and empirical models. Increase in the ambient pressure and nozzle diameter results in an increase of SMD at a distance 30, 45 and 60d$_{0}$, downstream of the nozzle, respectively.ely.