As a fluid machinery for piping liquid in the reactor cooling system, multi-stage centrifugal pump requires the structural dynamic stability against external dynamic excitation. This paper is concerned with the finite element analysis of its eigen behavior and seismic response to RRS(Required Response Spectrum) curves in the case of SSE (Safe Shutdown Earthquake). Through the finite element analysis, the major vibration characteristics of multi-stage centrifugal pump(MSCP) are investigated and seismic qualification based on the IEEE codes is executed. The numerical results show that the MSCP used in this study has enough seismic strength.