The objectives of this study are to present a proper mathematical model for a thermoelectric cooler equipped with the spacer and to investigate the effect of its geometries by heat transfer analysis. In order to enhance the efficiency of the thermoelectric cooler, the spacer is inserted between TEM (thermoelectric module) and cold plate. The theoretical results show that the COP (coefficient of performance) increases nonlinearly as high as 0.63 with increasing the depth of spacer and the depth of TEM and with decreasing the area of insulator