Databases are central to business information systems and RDBMS is most widely used for the database system. Normalization was designed to control various anomalies (insert, update, delete anomalies). However, normalized database design does not account for the tradeoffs necessary for performance. In this research, I model a database design method considering denormalization of duplicating attributes in order to reduce frequent join processes. This model considers response time for processing each select, insert, update, delete transaction, and for treating anomalies. A branch and bound method is proposed for this model.