R410A is considered as an alternative refrigerant to R22 for air conditioners. An experimental investigation was made to study the characteristics of the heat transfer and pressure drop for R410A flowing in a fin-and-tube heat exchanger used for commercial air-conditioning units. Experiments were carried out under the conditions of inlet refrigerant temperature of 6$0^{circ}C$ and refrigerant mass flux varying from 150 to 250 kg/$m^2$s for refrigerant side. The inlet air has dry bulb temperature of 35$^{circ}C$, relative humidity of 40% and air velocity varying from 0.68 to 1.6 m/s. Experiments show that air velocity decreased by 16% is needed for R410A than that of R22 for subcooling temperature of 5$^{circ}C$, which resulted in air-side pressure drop decrease of 15% for R410A as compared to R22. As a consequence, in order to provide the same design condition of a condenser, the fan requires lower electric-power consumption with R410A than that with R22.