The adapted scope of the Opening-covering-axis of Three-yin-three-yang can summary two parts. the first, former treatise of Gyeng-Lak emphasized the line structure by point and line but now we can understand expansible structure as not only line but also space of structure by the space structure of six-meeting. So the application of Gyeng-Lak can be various by extensive analysis of the Hand-three-yin-three-yang in Sky(Yang) including the Foot-three-yin-three-yang in Ground (Vin), even if the original text has limited examples. The second, former additional explanations of Hwangjenegyeng Sanghanlon by doctors can be profoundly analysis about the pathology and cure process of Three-yin-three-yang of human body. It has base on the metaphorically symbolized theory of Three-yin-three-yang. This is the Saeng-jang-shu-chang of So-yin, Tae-yang, Yang-myeng, So-yang. Tae-yin, Guel-yin in order. Also the circulation of Opening-covering-axis of Three-yin-three-yang has order in Tae-yang (Opening), Yang-myeng (Covering), So-yang (Axis), Tae-yin (Opening), Guel-yin (Covering), So-yin(Axis).