- 솔잎 발효액이 백서의 고지혈증 미치는 영향
- ㆍ 저자명
- 강대길,이윤미,오현철,문연자,이호섭,우원홍,Kang. Dae Gill,Lee. Yun Mi,Oh. Hyun Cheol,Mun. Yeun Ja,Lee. Ho Sub,Woo. Won Hong
- ㆍ 간행물명
- 동의생리병리학회지
- ㆍ 권/호정보
- 2003년|17권 1호|pp.140-145 (6 pages)
- ㆍ 발행정보
- 대한동의생리학회
- ㆍ 파일정보
- 정기간행물| PDF텍스트
- ㆍ 주제분야
- 기타
The present study was designed to examine whether the fermented extract using the leaves of Pinus densiflora (FPD), has an ameliorative effect on the lipid metabolism in rats with hyperlipidemia. The body weight gain was attenuated by the adminstration of either 1-dose (2 ml/kg/day) or 2-dose (4 ml/kg/day) of FPD for 2 weeks compared with that of control or hyperlipidemia rats, while blood glucose, systolic blood pressure, sGOT, and sGPT were not altered. Serum total cholesterol, LDL-cholesterol, and athelosclerotic index were partially restored by the administration of 2-dose of FPD in rats with hyperlipidemia without changes of serum HDL-cholesterol, total lipid, and triglyceride concentration. The FPD also partially ameliorated renal functional parameters including plasma cleatinine and creatinine clearance which were attenuated in rats with hyperlipidemia. These results suggest that FPD has an ameliorative effect on the lipid metabolism and renal function in rats with hyperlipidemia.