- 포황이 흰쥐의 식이성 고지혈증 치료에 미치는 영향
- ㆍ 저자명
- 신형섭,김규열,김호현,서일복,Shin. Hyung Seop,Kim. Gyu Yeol,Kim. Ho Hyun,Seo. Il Bok
- ㆍ 간행물명
- 동의생리병리학회지
- ㆍ 권/호정보
- 2003년|17권 1호|pp.225-229 (5 pages)
- ㆍ 발행정보
- 대한동의생리학회
- ㆍ 파일정보
- 정기간행물| PDF텍스트
- ㆍ 주제분야
- 기타
In Oriental Medicine, hyperlipidemia is considered as the phlegm stagnancy(痰飮) and blood stasis(瘀血). Typhae Pollen helps remove blood stasis and hemorrhage and it also has an effect of relieving pains caused by blood stasis. The purpose of this study is to investigate the curative effects of Typhae Pollen on diet-induced hyperlipidemia in rats. Thirty-two rats were divided into normal, control and treated group. Control and treated group were fed with 1.5% cholesterol diet during 4 weeks, and fed with normal diet during next 4 weeks. Treated group was also administrated with extract of Typhae Pollen during last 4 weeks. Blood samples were collected from each of animals at 4, 6 and 8weeks, and used for the blood chemical analysis. Animals were sacrificed at 8 weeks, and chemical analysis was performed on the collected liver samples. The serum total cholesterol(47.82±2.03㎎/㎗), LDL-cholesterol(11.09±1.27㎎/㎗), HDL-cholesterol (19.64±1.23㎎/㎗), triglyceride(85.09±3.48㎎/㎗) values of treated group were significantly decreased compared with the serum total cholesterol(73.73±5.34㎎/㎗), LDL-cholesterol(22.09±3.09㎎/㎗), HDL-cholesterol(25.18±1.45㎎/㎗l), triglyceride(124.27±6.72㎎/㎗) values of control group at 8weeks. The liver total cholesterol and triglyceride values of treated group show no statistically significant differency compared with those values of control group. On the basis of these results, it is confirmed that Typhae Pollen has the curative effects on the hyperlipidemia in rats induced by hyper-cholesterol diets.