- 음파영동 경피투과에 의한 Lidocaine Gel의 마취효과
- ㆍ 저자명
- 김태열,최석주,이준희,김영일,정규호,Kim. Tae-Youl,Choi. Sug-Ju,Lee. Joon-Hee,Kim. Young-Il,Chung. Kyu-Ho
- ㆍ 간행물명
- 대한임상전기생리학회지
- ㆍ 권/호정보
- 2003년|1권 2호|pp.11-19 (9 pages)
- ㆍ 발행정보
- 대한임상전기생리학회
- ㆍ 파일정보
- 정기간행물| PDF텍스트
- ㆍ 주제분야
- 기타
The purpose of this study investigated the anesthetic effects of lidocaine gel by phonophoretic transdermal delivery. The anesthetic effects were evaluated by two aspects as quantitative sensory testing and sensory nerve conduction study. Twelve healthy males(aged $23.25{pm}2.09$ years) were studied. Exclusion criteria were ; pain, history of sensory disturbances and skin conditions in the areas to be examined. The subjects were divided into two groups; group I(lidocaine gel without ultrasound) and group II(lidocaine gel with ultrasound). The following results were obtained; 1. In changes of tactile threshold and electrical pain threshold, all groups were significantly increased(p<0.05). 2. In changes of electrical pain threshold, it was significantly differenced between the groups(p<0.05). We conclude that the transdermal delivery of lidocaine gel by phonophoresis has a possibility to use for surface anesthesia and the pain control of the superficial tissue.