Purpose: This study was conducted to identify the relationship between climacteric symptoms and sexual satisfaction in middle-aged women. Method: Self-selection was used to recruit, for the study, 272 middle-aged women between 40 and 59 years of age from 2 metropolitan areas and 2 provinces in Korea. The questionnaire included information on demographic characteristics, climacteric symptoms and sexual satisfaction. Result: The results are as follows: 1. The mean/item climacteric symptom score was 1.91 and the mean sexual satisfaction score was 38.19.2. Climacteric symptoms were significantly influenced by age, education, economic status, frequency of abortions and menopausal status. Sexual satisfaction was influenced significantly by age, education, economic status and menopausal status. 3. There was a significant negative correlation between climacteric symptoms and sexual satisfaction (r=-.24, p =.0002). Conclusion: Sexuality should be considered when developing nursing strategies for middle-aged women, especially when dealing with climacteric symptoms.