We investigated the effect of Qi therapy (QT) on peripheral blood pressure (PBP), glucose, lactate dehydrogenase (LDH) and cortisol concentrations. Fourteen college students participated in receiving QT and placebo treatment. There were significant differences in embedding dimension of PBP. Plasma cortisol concentrations during QT were significantly lower than during control sessions (P<O.05). These findings suggest that QT may reduce stess level and stabilize the autonomic nervous system. Whether QT have permanent effects and effects in patients need controlled and prospective studies.