This report describes 61 studies related to the use of Semen Armeniacae Amarum main blended prescriptions from Donguibogam. The following conclusions were reached through investigations on the prescriptions that use Semen Armeniacae Amarum as a key ingredient. Semen Armeniacae Amarum blended prescriptions are utilized for 16 therapeutic purposes, for example, in symptoms of cough, excrements, wind, and pediatrics. In particular, 52.46% of the prescriptions appear in the chapter of cough, and 9.84% of those appear in the chapter of excrements. Prescriptions that utilize Semen Armeniacae Amarum as the main ingredient are used in the treatment of cough, asthma, lung disease, and constipation, and they are also used for treating 15 different types of diseases. Semen Armeniacae Amarum is used in pathogenic factors such as wind, wind with cold, and wind with moisture, in pathologies related to lung and digestive systems, and in those related to weakness, extravasated blood, and alcoholic drink-food. The actual amount of Semen Armeniacae Amarum blended has ranged at a wide variety of amounts from 5 pun to 5 don. 47.62% of the prescriptions used 1 don. When Semen Armeniacae Amarum is combined with base prescriptions such as Samyotang, Banhaenghwan, ljintang, etc and Herba Ephedrae, Rhizoma Pinelliae, and Pericarpium Citri Reticulatae, it ceases cough and asthma. In addition, when Semen Armeniacae Amarum is combined with Fructus Ponciri Seu Aurantii and Fructus Cannabis, it brings a relief in constipation.