A previous study evaluated the seismic response of typical multi-span simply supported (MSSS) and multi-span continuous (MSC) steel-girder bridges in the central and southeastern United States. The results showed that the bridges were vulnerable to damage resulting from impact between decks, and large ductility demands on nonductile columns. Furthermore, fixed and expansion bearings were likely to fail during strong ground motion. In this paper, several retrofit measures to improve the seismic performance of typical multi-span simply supported and multi-span continuous steel girder bridges are evaluated, including the use of elastomeric bearings, lead-rubber bearings, and restrainer cables. It is determined that iead-rubber bearings are the most effective retrofit measure for reducing the seismic vulnerability of typical bridges. While isolation provided by elastomeric bearings limits the forces into the columns, the added flexibility results in pounding between decks in the MSSS steel-girder bridge. Restrainer cables, which are becoming a common retrofit measure, are only moderately effective in reducing the seismic vulnerability of MSSS and MSC steel girder bridges.