This paper describes conceptual development and idea-verification of a sub-miniature portable cooler which dose not necessitate any pre-cooling nor any external energy supply. The basic principle of the cooling mechanism is the vaporization of water and sub-sequent cooling due to the evaporative latent heat loss. In this work, the vaporization of the water is stimulated by desiccant material to improve the cooling effect. The evaporative cooling caused by the desiccant is modeled and analyzed considering the sorption characteristics of the desiccant. In addition, the portable cooler is fabricated in the shape of a thin pad, and its cooling characteristics are tested and compared with the analytic results.