The global stiffnesses and vibration characteristics of vehicle structures are mainly influenced by local stiffnesses of the joint structures consisted of complicated thin-walled panels. In this paper, the parametric study for the stiffnesses of the center pillar-roof rail joint of vehicle structure is performed through the linear static analysis. The analysis result shows that the reinforcement panel much affects the joint stiffness of out-plane direction (i.e., z-direction). And also, the flange radius and width of the joint structure much affect the Joint stiffness of out-plane direction. The study shows that vehicle joint stiffnesses can be effectively determined in designing vehicle structure through the parametric study.