Synthesis of 2 -Azidoethyl Trisaccharide,$alpha-D-Gal-(1 igharrow2)-6d-alpha-D- Altro-Hepp-(1 ightarrow3)-eta$-D-GlcNAc, an O-Antigenic Repeating Unit of C.jejuni O:23 and O:36

Synthesis of 2 -Azidoethyl Trisaccharide,$alpha-D-Gal-(1 igharrow2)-6d-alpha-D- Altro-Hepp-(1 ightarrow3)-eta$-D-GlcNAc, an O-Antigenic Repeating Unit of C.jejuni O:23 and O:36

ㆍ 저자명: Yun. Mi-Kyung,Yoon. Shin-Sook,Shin. Young-Sook,Chun. Keun-Ho,Namshin.. Jeong. E
ㆍ 간행물명: Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
ㆍ 권/호정보: 2004년|27권 2호|pp.143-150 (8 pages)
ㆍ 발행정보: 대한약학회
ㆍ 파일정보: 정기간행물|
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ㆍ 주제분야: 기타

이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.

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기타언어초록

A trisaccharide, the O-antigenic repeating unit of C. jejuni serotype O:23 and O:36, was synthesized as a 2 -azidoethyl glycoside by block addition of perbenzylated thiogalactoside donors to $alpha$-altroHepp-(1$ ightarrow$3)-GlcNPhth disaccharide acceptor in presence of IDCP promoter. The $alpha$-linked altroheptopyranoside moiety in the glycosyl acceptor was effectively prepared by Swern oxidation of $alpha$-mannohepp-(1$ ightarrow$3)-GlcNPhth disaccharide followed by mild reduction with1 $NaCNBH_3$.

키워드

Campylobacter jejuni O-Antigenic repeating unit $alpha$-AltroHepp-(1$ ightarrow$3)-GlcNPhth disaccharide acceptor 2 -Azidoethyl trisaccharide

다운URL