This paper presents the comparison results of some kinds of control method in circumstance of eccentric load. The plant to be controlled is a computed tomography(CT) driven by a permanent magnet synchronous motor. In a CT system, many units are attached on the rotationally part of a gantry such as x-ray tube, detector, heat exchanger, and data acquisition unit etc. Therefore keeping many components to balance which have different weight is not easy; this is inescapable problem in the all CT systems. To solve this problem against eccentric load, some kinds of control method have been compared and analysed by using protype CT. From the experimental results it is vilified that the CT drive system with model reference control method indicates higher speed regulation ability regardless of variable eccentric weight and uncertain position, and also in the limit condition of constant eccentric weight and fixed position, the compensation method with sinusoidal form is a strong candidate in view of speed ripple reduction.