$sigma^{B}$ plays an important role in both osmoprotection and proper differentiation in Streptomyces coelicolor A3(2). We searched for candidate members of the $sigma^{B}$ regulon from the genome database, using the consensus promoter sequence (GNNTN$_{14-16}$GGGTAC/T). The list consists of l15 genes, and includes all the known $sigma^{B}$ target genes and many other genes whose functions are related to stress protection and dif-ferentiation.